My name is Silvia and I live in La Plata, Buenos Aires. When I turned 47, I was diagnosed with CADISIL disease (today I am 52). CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common form of hereditary stroke disorder, and is thought to be caused by mutations of the Notch 3 gene on chromosome 19.
The disease belongs to a family of disorders called the Leukodystrophies. The most common clinical manifestations are migraine headaches and transient ischemic attacks or strokes, which usually occur between 40 and 50 years of age, although MRI is able to detect signs of the disease years prior to clinical manifestation of disease.
The primary symptoms for me are strong headache and lost partial recent memory. My father and uncles all suffered from CADASIL as well. In 2012, after nearly 28 years as a doctor in biology, I retired from teaching. Today, my hobby is the basketery.
I have hope in my genes! For more information on CADASIL, visit the CADASIL Foundation.