Cerebral Sclerosis Similar to Pelizaeus-Merzbacher Disease


Type of disease: Rare conditions

Cerebral sclerosis also known as Schilder’s disease, is a rare disorder that affects the central nervous system and is thought to be a type of multiple sclerosis. Generally, multiple sclerosis affects the flow of information within the brain and between the brain and the body. Common symptoms of cerebral sclerosis specifically include weakness on one side of the body, slow movement, seizures, speech problems, hearing problems, memory problems, personality changes, nutrition problems, and changes in breathing, blood pressure, and heart rate. The overall signs are different with each individual. The neurological signs of the disorder are usually develop and get worse over time. This condition usually begins in childhood and sometimes during young adulthood. Specifically, the condition most often occurs in males between the ages of 7 and 12.

The cause of cerebral sclerosis is not entirely understood, though the condition often occurs after individuals have an infection. The first signs of the condition usually include headaches, feelings of discomfort, and fever. In cerebral sclerosis, the nerve signals cannot be transmitted as quickly because a substance called myelin gets degraded in the brain and spinal cord. Usually, myelin functions to help speed up nerve signals, so when myelin is degraded as it is in this condition, the signals do not get transmitted as they should.

In diagnosing cerebral sclerosis, there is specific criteria that physicians look for. Particularly, they will look for lesions in an area of the brain called the semioval center, and around the hemispheres of the brain. A type of drug called corticosteroids is often used in the treatment of this condition. Other options to alleviate symptoms include physical and occupational therapy, and improved diet.

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