Cleft Palate Lateral Synechia Syndrome


Type of disease: Rare conditions

Cleft palate-lateral synechia syndrome (CPLS) is a genetic combination of symptoms, or a syndrome, that is present at birth. Cleft lip and/or palate is the incomplete formation of the lip and mouth, creating a gap in the upper lip as well as a small hole in the roof of the mouth. Lateral synechia describes the joining of parts of the roof of the mouth with parts of the tongue and floor of the mouth. This may be a dominant genetic disorder, meaning parents have a high likelihood of passing it to their children, however, this research is not conclusive. Opening the mouth wide enough to eat presents a major challenge in patients with CPLS. When the fetus is born with these symptoms, the doctor will usually use a small flexible camera to inspect the back of the throat and mouth areas. The team managing the condition may then proceed to remove the connections and fix the cleft lip and/or palate with surgery.

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