Cold Contact Urticaria


Type of disease: Rare conditions

Cold contact urticaria, often referred to as simply cold urticaria, is a chronic, reactive skin disorder. Major symptoms may include abnormal reddening of the skin, hives, swelling and itching after exposure of the skin to cold, cold water, and cold objects. Symptoms typically develop within two to five minutes after exposure to the triggering substance or situation and last for one to two hours. The cause of cold contact urticaria isn’t clear. Some cases are secondary to underlying conditions (blood conditions or infectious diseases).  As much as possible, people with cold contact urticaria should avoid exposure to cold air as well as cold water. Treatment for cold contact urticaria may include antihistamines taken before cold exposure. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.

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