Type of disease: Rare conditions
Eosinophilic fasciitis is a very rare condition in which muscle tissue underneath the skin, called fascia, becomes swollen and thick. Rapid swelling can occur in the hands, arms, legs, and feet. People with this condition have a buildup of eosinophils, a type of white blood cell, in the affected fascia and muscles. The exact cause of this condition is unknown. Fewer than 300 cases have been reported in the past 35 years. Eosinophilic fasciitis is similar in appearance to scleroderma but is not related. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.