Esthesioneuroblastoma
Synonyms: Olfactory neuroblastoma
Esthesioneuroblastoma (ENB) is a rare malignant neoplasm of the sinonasal cavity arising from the basal layers of olfactory neuroepithelial cells in the superior nasal vault which usually occurs in the 5th to 6th decades of life and is characterized clinically by non-specific symptoms such as progressive ipsilateral nasal block sinusitis facial pain intermittent headaches hyposmia/dysosmia rhinorrhea and epistaxis as well as proptosis diplopia and excessive lacrimation due to orbital extension. With early treatment and in the absence of distant metastases ENB appears to have a good prognosis (compared to other superior nasal malignancies) despite a high rate of cervical metastases.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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