Type of disease: Rare conditions
Locked-in syndrome is a rare neurological disorder. Signs and symptoms include paralysis of voluntary muscles in the body, except for those that control eye movement.Individuals with locked-in syndrome are conscious and can think and reason, but are unable to speak or move. It may be caused by brain stem stroke, traumatic brain injury, diseases of the circulatory system, diseases that destroy the myelin sheath surrounding nerve cells, or medication overdose. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.