Severe combined immunodeficiency, x-linked
Type of disease: Genetic, X-linked | Autoimmune | Rare conditions
X-linked severe combined immunodeficiency (SCID) is an inherited disorder of the immune system. It almost always affects boys. Signs and symptoms include severe, recurring infections, chronic diarrhea, skin rashes, and slow growth. Without treatment, people with this condition usually do not live past infancy. It is caused by mutations in the IL2RG gene. It is inherited in an X-linked recessive fashion. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.