Acquired prothrombin deficiency
Synonyms: Acquired hypoprothrombinemia
A rare hemorrhagic disorder characterized by decreased factor II plasma levels in association with severe liver disease vitamin K deficiency or vitamin K antagonist treatment or in the context of other conditions such as systemic lupus erythematosus primary antiphospholipid syndrome or infections. Patients present with increased bleeding tendency leading to easy bruising frequent nosebleeds hemorrhaging after surgery or trauma and heavy menstrual bleeding among others. Joint bleeding is uncommon.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Acquired prothrombin deficiency?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Clinical Trials
For a list of clinical trials in this disease area, please click here.