Acute bilirubin encephalopathy
Synonyms: ABE | Acute kernicterus
A rare neurologic disease characterized by lethargy hypotonia poor feeding opisthotonus and a typical high-pitched cry due to bilirubin accumulation in the globus pallidus sub-thalamic nuclei and other brain regions resulting from severe neonatal unconjugated hyperbilirubinemia. Onset of symptoms is typically within the first three to five days of life. Additional features include fever apnea seizures and coma. Especially respiratory failure or refractory seizures may lead to a fatal outcome.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version June 2023.
Newly diagnosed with
Acute bilirubin encephalopathy?
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Moonshots for Unicorns
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Patient Advocate Foundation
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advocate for Rare disease patients and their families
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Youth and Women for Opportunities-YWOU an organization that we represent is patient organization re-presentative, patient and institution and individual capacity builder supporting PLWRD’s to obtain diagnosis, treatment and drugs for those suffering consequences of being undiagnosed or misdiagnosed and lack treatment and those who lack precise diagnosis for rare, orphan and undiagnosed diseases preventing PLWRD’s accessing the most adapted care, treatment or surgery, have delayed access to the most appropriate care, treatment or surgery
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For a list of clinical trials in this disease area, please click here.