Acute infantile liver failure-multisystemic involvement syndrome
A rare genetic parenchymal hepatic disease characterized by acute liver failure that occurs in the first year of life which manifests with failure to thrive hypotonia moderate global developmental delay seizures abnormal liver function tests microcytic anemia and elevated serum lactate. Other associated features include hepatosteatosis and fibrosis abnormal brain morphology and renal tubulopathy. Minor illness exacerbates deterioration of liver failure.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
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Acute infantile liver failure-multisystemic involvement syndrome?
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Advocacy Organizations
Global Liver Institute
To improve the lives of individuals and families impacted by liver disease through promoting innovation, encouraging collaboration, and scaling optimal approaches to help eradicate liver diseases.
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
Clinical Trials
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