Acute necrotizing encephalopathy of childhood

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Acute necrotizing encephalopathy of childhood

Synonyms: ANEC | Isolated ANE | Isolated acute necrotizing encephalopathy

A rare neurologic disease characterized by a rapid onset of seizures an altered state of consciousness neurologic decline and variable degrees of hepatic dysfunction following a respiratory or gastrointesitnal infection (e.g. mycoplasma influenza virus) in a previously healthy child. Brain MRI of patients reveals bilateral multiple symmetrical lesions predominantly observed in thalami and brainstem but also in periventricular white matter and cerebellum in some cases.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: // Data version September 2023.

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Advocacy Organizations

Aicardi-Goutieres Syndrome Advocacy Association

AGSAA is a global coalition of deeply dedicated parent advocates working alongside clinicians, researchers, and scientists. We are united in our desire to improve the lives of individuals and families living with Aicardi-Goutières Syndrome and those yet to be diagnosed. Everything we do reflects a sense of urgency to rescue patient potential and preserve quality of life through accelerating research and providing timely emotional and educational support alongside evolving clinical care recommendations to affected families.

Clinical Trials

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