Synonyms: Blepharochalasis-double lip syndrome
A very rare syndrome characterized by a combination of blepharochalasis double lip and non-toxic thyroid enlargement (seen in 10-50% of cases) although the occurrence of all three signs at presentation is uncommon. Hypertrophy of the mucosal zone of the lip with persistence of the horizontal sulcus between cutaneous and mucosal zones gives an appearance of double lip with the upper lip being frequently involved. Blepharochalasis or episodic edema of eyelid appears around puberty is present in 80% of cases is usually bilateral and can rarely lead to vision impairment and other ocular complications. Most cases are sporadic but familial cases (with a possible autosomal dominant inheritance) have also been reported.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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