Autosomal dominant spastic paraplegia type 10

Get in touch with RARE Concierge.

Contact RARE Concierge

Autosomal dominant spastic paraplegia type 10

Synonyms: SPG10

A rare hereditary spastic paraplegia that can present as either a pure or complex phenotype. The pure form is characterized by lower limb spasticity hyperreflexia and extensor plantar responses presenting in childhood or adolescence. The complex form is characterized by the association with additional manifestations including peripheral neuropathy with upper limb muscle atrophy moderate intellectual disability and parkinsonism. Deafness and retinitis pigmentosa have also been reported.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version March 2024

Newly diagnosed with
Autosomal dominant spastic paraplegia type 10?

Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.

Get Concierge Help

Clinical Trials

For a list of clinical trials in this disease area, please click here.