Axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy

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A rare acquired peripheral neuropathy characterized by symmetric slowly progressive predominantly sensory neuropathy mostly limited to the legs with numbness and paresthesia of the distal leg and mild imbalance. Some patients may experience pain weakness of foot dorsiflexion mild proximal leg weakness and/or upper limb involvement. The majority of patients have IgG monoclonal gammopathy. Systemic illnesses are absent in most cases.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version July 2024

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Axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy?

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Advocacy Organizations

Project CASK

VISION Project CASK believes in a world free of the life limitations and debilitating effects of CASK gene disorders. ​MISSION To accelerate breakthroughs in research to develop treatments and a cure for CASK gene disorders. ​VALUES Collaboration. Transparency. Urgency.

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Clinical Trials

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