Carcinosarcoma of the corpus uteri

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Synonyms: Malignant mixed Müllerian tumor of the corpus uteri | Mixed Müllerian cancer of corpus uteri | Uterine carcinosarcoma

Carcinosarcoma of the corpus uteri is a rare malignant mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements. It may present with vaginal bleeding abnormal vaginal discharge abdominal pain and/or pelvic mass with a polypoid tumor sometimes protruding through the cervical canal. Association with Tamoxifen therapy long-term unopposed estrogen use and previous pelvic radiotherapy has been reported.

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