Congenital syphilis
Synonyms: MTCT of syphilis | Mother-to-child transmission of syphilis
A rare teratologic disease caused by vertical transmission of the spirochete Treponema pallidum from an infected mother to the fetus characterized by early congenital syphilis during the first two years of life (maculopapular rash progressing to desquamation hepatosplenomegaly osteochondritis snuffles and iritis) followed by late congenital syphilis with the classic Hutchinson’s triad of Hutchinson’s teeth interstitial keratitis and eighth nerve deafness. Additional signs may include saddle nose saber shins seizures and mental retardation. Congenital syphilis can also result in stillbirth neonatal death and nonimmune hydrops.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Congenital syphilis?
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