Discoid lupus erythematosus

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Discoid lupus erythematosus

A rare form of chronic cutaneous lupus erythematosus characterized by erythematous scaly papules and plaques preferentially occurring on sun-exposed skin areas (scalp face and ears) and exhibiting follicular plugging pigmentary changes and central atrophy scarring and telangiectasia. Skin biopsy shows a perivascular and periadnexal lymphocytic infiltrate and involvement of the dermoepidermal junction with thickening of the basement membrane and vacuolar degeneration of the basal cells. A small percentage of patients may develop systemic lupus erythematosus.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.

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Discoid lupus erythematosus?

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Advocacy Organizations

the fairy goddess mother project inc

The Fairy Goddess Mother Project is dedicated to increasing awareness of Vulvar Lichen Sclerosus (VLS), providing financial assistance to women needing treatment, and supporting patient’s efforts to participate in clinical trials.

the fairy goddess mother project inc

The Fairy Goddess Mother Project is dedicated to increasing awareness of Vulvar Lichen Sclerosus (VLS), providing financial assistance to women needing treatment, and supporting patient’s efforts to participate in clinical trials.

Clinical Trials

For a list of clinical trials in this disease area, please click here.