Discoid lupus erythematosus
A rare form of chronic cutaneous lupus erythematosus characterized by erythematous scaly papules and plaques preferentially occurring on sun-exposed skin areas (scalp face and ears) and exhibiting follicular plugging pigmentary changes and central atrophy scarring and telangiectasia. Skin biopsy shows a perivascular and periadnexal lymphocytic infiltrate and involvement of the dermoepidermal junction with thickening of the basement membrane and vacuolar degeneration of the basal cells. A small percentage of patients may develop systemic lupus erythematosus.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Discoid lupus erythematosus?
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Advocacy Organizations
The Fairy Goddess Mother Project Inc.
The Fairy Goddess Mother Project is a 501(c)(3) Non-profit Rare Disease Patient Advocacy Organization dedicated to increasing awareness of the little-known, often misdiagnosed disease Vulvar Lichen Sclerosus (VLS), providing financial assistance to afflicted women in need of treatment, and supporting patients’ efforts to participate in clinical trials.
Clinical Trials
For a list of clinical trials in this disease area, please click here.