Duplication of the pituitary gland

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Duplication of the pituitary gland

Synonyms: DPG-plus syndrome | Duplication of the pituitary gland-plus syndrome | Hypophyseal duplication

A rare midline cerebral malformation characterized by duplicated pituitary stalks and/or glands within duplicated sella. Patients may present various degrees of facial dysmorphism and endocrine abnormalities including precocious puberty hypogonadism hypothyroidism and/or hyperprolactinemia as well as associated congenital anomalies such as clift lip/palate bifid nasal bridge/tongue/uvula hypothalamic enlargement with or without hamartoma nasopharyngeal tumors corpus callosum agenesis/hypoplasia basilar artery duplication and/or vertebral defects (in particular duplication of the odontoid process).

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version March 2024

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