Erythema multiforme major

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Erythema multiforme major

Synonyms: Erythema exsudativum multiforme majus | Erythema multiforme majus

A rare skin disease characterized most typically by targetoid papules with 3-rings of concentric color variation (dark center surrounded by lighter pink ring and an outer red ring) symmetrically distributed on the extensor surfaces of the extremities or more diffuse accompanied by 2 or more mucosal involvements (erosions of the oral genital anal mucosa conjunctivitis pseudomembranes). The condition is commonly proceeded by prodromal symptoms of malaise fever and myalgias and is usually self-limiting resolving within a few weeks; although there is a risk of recurrence. The disease is mostly triggered by infectious agents (herpes virus mycoplasma pneumoniae) but a subset of patients have auto-antibodies targeting plakins. Rare cases of severe mucosal sequelae have been described.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version December 2023

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Erythema multiforme major?

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