Familial median cleft of the upper and lower lips
A rare developmental defect during embryogenesis characterized by incomplete median clefts of both the lower lip (limited to the vermilion with no muscle involvement) and upper lip (with muscle involvement) double labial frenulum and fusion of the upper gingival and upper labial mucosa (resulting in a shallow upper vestibular fold) in addition to poor dental alignment and increased interdental distance between the lower and upper median incisors.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
Newly diagnosed with
Familial median cleft of the upper and lower lips?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
For a list of clinical trials in this disease area, please click here.