Familial median cleft of the upper and lower lips

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Familial median cleft of the upper and lower lips

A rare developmental defect during embryogenesis characterized by incomplete median clefts of both the lower lip (limited to the vermilion with no muscle involvement) and upper lip (with muscle involvement) double labial frenulum and fusion of the upper gingival and upper labial mucosa (resulting in a shallow upper vestibular fold) in addition to poor dental alignment and increased interdental distance between the lower and upper median incisors.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024

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