Familial medullary thyroid carcinoma

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Familial medullary thyroid carcinoma

Synonyms: Familial MTC

A rare thyroid tumor characterized by a malignant neoplasm derived from the calcitonin-secreting parafollicular C-cells of the thyroid and occurring familially but not as a component of multiple endocrine neoplasia syndromes. The commonly multifocal bilateral nodules are typically located at the junction of the upper and middle thirds of the thyroid lobes. Clinically patients may present with diarrhea flushing or weight loss caused by excessive secretion of calcitonin by the tumor. In rare cases the tumor can also cause Cushing syndrome due to ectopic corticotropin production.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.

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Familial medullary thyroid carcinoma?

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My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

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