Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome
Synonyms: GLOW syndrome
Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome is a rare genetic overgrowth syndrome characterized by global developmental delay macrosomia with subsequent somatic overgrowth bilateral cystic lung lesions congenital nephromegaly and bilateral Wilms tumor. Craniofacial dysmorphism includes macrocephaly frontal bossing large anterior fontanelle mild hypertelorism ear pit flat nasal bridge anteverted nares and mild micrognathia. Additional features may include brain and skeletal anomalies enlarged protuberant abdomen fat pads on dorsum of feet and toes and rugated soles with skin folds as well as umbilical/inguinal hernia and autistic behavior.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
Newly diagnosed with
Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
My Faulty Gene
My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.
My Little Sunshine Foundation
My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.
Educate and provide resources to POC with Rare Cancers
Help Hope Live
Help Hope Live assists individuals living with catastrophic injuries and illnesses to fundraise toward their medical expenses and related costs.
For a list of clinical trials in this disease area, please click here.