Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome

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Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome

Synonyms: GLOW syndrome

Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome is a rare genetic overgrowth syndrome characterized by global developmental delay macrosomia with subsequent somatic overgrowth bilateral cystic lung lesions congenital nephromegaly and bilateral Wilms tumor. Craniofacial dysmorphism includes macrocephaly frontal bossing large anterior fontanelle mild hypertelorism ear pit flat nasal bridge anteverted nares and mild micrognathia. Additional features may include brain and skeletal anomalies enlarged protuberant abdomen fat pads on dorsum of feet and toes and rugated soles with skin folds as well as umbilical/inguinal hernia and autistic behavior.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version May 2024

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Cache DNA

At Cache, we are on a mission to store the biomolecules of today in order to unlock the possibilities of tomorrow. Our vision is to create a scalable, sustainable, and standardized platform for reliable storage and access of biomolecules by combining chemistry, biology, automation, and computational tools to support patient advocacy groups worldwide and better connect samples to insights.

My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

My Little Sunshine Foundation

My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.


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