High-grade neuroendocrine carcinoma of the corpus uteri
Synonyms: High-grade neuroendocrine carcinoma of the uterine corpus | Poorly differentiated neuroendocrine carcinoma of the corpus uteri | Poorly differentiated neuroendocrine carcinoma of the endometrium
High-grade neuroendocrine carcinoma of the corpus uteri is an extremely rare aggressive primary uterine neoplasm originating from neuroendocrine cells scattered within the endometrium characterized macroscopically by a bulky frequently polypoid mass with abundant necrosis located in the uterus and histologically by rosette-like and cord-like structures consisting of small rounded cells with oval nuclei and scarce cytoplasm. Patients often present with dysfunctional uterine bleeding pelvic or abdominal mass and especially in later stages of the disease abdominal pain. Symptomatic metastatic spread or symptoms related to a paraneoplastic syndrome such as retinopathy or Cushing syndrome due to ectopic ACTH production may be associated.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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High-grade neuroendocrine carcinoma of the corpus uteri?
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Neuroendocrine Cancer Awareness Network Inc
The Neuroendocrine Cancer Awareness Network (NCAN) is a non-profit organization dedicated to raising awareness of Neuroendocrine Cancer, providing support for caregivers and people with NETs, and funding for NET cancer research. Since 2003, it has been our mission, or as we like to say, our passion, to educate and support the NET community as a whole. That’s our thing.
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My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.
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