Hypertension due to gain-of-function mutations in the mineralocorticoid receptor
Synonyms: Early-onset hypertension with exacerbation in pregnancy | Pseudohyperaldosteronism type 2
A rare genetic cause of hypertension characterized by severe early-onset therapy-resistant hypertension due to a gain-of-function mutation in the mineralocorticoid receptor. The condition is associated with suppressed plasma renin activity and low serum aldosterone levels and is markedly exacerbated during pregnancy.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Hypertension due to gain-of-function mutations in the mineralocorticoid receptor?
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