Hypertrophic or verrucous lupus erythematosus
Hypertrophic or verrucous lupus erythematosus is a rare type of chronic cutaneous lupus erythematosus characterized by the appearance of lesions on sun-exposed areas (frequently the extensor surfaces of forearms face upper trunk) which vary from squamous violet painful papules and blackish hyperkeratotic ulcers to depigmented atrophic plaques on the back hyperkeratotic papules on upper extremities and disseminated keratoacanthoma-like papulonodular verrucous lesions. Classic discoid lesions and squamous cell carcinoma may be associated. Histopathology reveals follicular plugging liquefactive basal layer degeneration and a perivascular lymphocytic infiltrate.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Hypertrophic or verrucous lupus erythematosus?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
The Fairy Goddess Mother Project Inc.
The Fairy Goddess Mother Project is a 501(c)(3) Non-profit Rare Disease Patient Advocacy Organization dedicated to increasing awareness of the little-known, often misdiagnosed disease Vulvar Lichen Sclerosus (VLS), providing financial assistance to afflicted women in need of treatment, and supporting patients’ efforts to participate in clinical trials.
Clinical Trials
For a list of clinical trials in this disease area, please click here.