Immune-mediated necrotizing myopathy

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Immune-mediated necrotizing myopathy

Synonyms: Anti-HMG-CoA myopathy | Anti-SRP myopathy | Autoimmune necrotizing myositis | IMNM | Immune myopathy with myocyte necrosis | NAM

A rare form of idiopathic inflammatory myopathy characterized by acute or subacute severe symmetrical proximal muscle weakness usually associated with muscle-specific antibodies (anti-HMGCR or anti-SRP). Histopathological characteristics include myocyte necrosis and regeneration without significant inflammation and C5b-9 deposition on non-necrotic myofibers.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version December 2023

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Immune-mediated necrotizing myopathy?

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Advocacy Organizations

Association Aux Pas du Coeur

Our organization wants to raise awareness and recognize rare diseases in Côte d'Ivoire. Our mission is to: Raising awareness and campaigning to help with the diagnosis and free therapeutic care of patients. Request and/or contribute to actions relating to the training of the medical profession so that doctors are able to make a final diagnosis and ensure the continuous follow-up of patients. Create a patient registry to establish very precise statistics of rare diseases in Côte d'Ivoire. Create a close-knit patient community. Break the isolation and despair of sick people and their families. Open up to the world and actively contribute to international research aimed at treatments.

Clinical Trials

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