Immunodeficiency due to a classical component pathway complement deficiency

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Immunodeficiency due to a classical component pathway complement deficiency

Synonyms: Immunodeficiency due to C1, C4, or C2 component complement deficiency | Immunodeficiency due to an early component of complement deficiency

Immunodeficiency due to a classical component pathway complement deficiency is a primary immunodeficiency due to a deficiency in either complement components C1q C1r C1s C2 or C4 characterized by increased susceptibility to bacterial infections particularly with encapsulated bacteria and increased risk for autoimmune disease. Most commonly these include systemic lupus erythematosus (SLE) SLE-like disease Henoch-Schonlein purpura polymyositis and arthralgia. Disease severity is variable and dependent on the complement affected.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: // Data version September 2023.

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Advocacy Organizations

Ukrainian Association of Pediatric Immunology

Development of pediatric and clinical immunology in Ukraine. Raising awareness of inborn errors of immunity in Ukraine and rare immune diseases; Advocacy campaigns supporting patients with rare immune diseases and their treatment plans; Scientific research; Sharing knowledge about immunoprophylaxis; Advocacy campaigns supporting immunoprophylaxis.

Accessia Health

Accessia Health pioneered the patient assistance model for people living with chronic medical conditions. We provide financial assistance to pay for prescriptions, medical treatments and expenses, travel and insurance premiums. Our program services include healthcare education, specialized legal services, and case management. We’re leveraging our three decades of our entrepreneurial spirit to expand patient assistance support to serve today’s healthcare consumers. Serving diverse populations is our #1 goal and we seek partners who share our belief that all people deserve to have access to healthcare. Over $1.1 billion has been distributed to patients throughout the country, helping them navigate their way through the complexities of the healthcare system. You can help us do even more.

Clinical Trials

For a list of clinical trials in this disease area, please click here.