Isolated corpus callosum agenesis
A rare non-syndromic cerebral malformation characterized by congenital partial or complete absence of the corpus callosum. Patients are often asymptomatic but may also present with intellectual disability visual impairment delayed speech development seizures feeding difficulties impaired hand-eye coordination and behavioral abnormalities. Patients may have a normal intelligence quotient while exhibiting specific cognitive deficits such as reduced interhemispheric transfer of sensorimotor information reduced cognitive processing speed and deficits in complex reasoning and novel problem-solving.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
Newly diagnosed with
Isolated corpus callosum agenesis?
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National Organization for Disorders of the Corpus Callosum
The NODCC has become the leading organization for disorders of the corpus callosum seeking to raise the profile, understanding and acceptance of these disorders through education, networking, advocacy, and being a catalyst for research.
Moonshots for Unicorns
Curing single-gene disorders
COMBINEDBrain is a consortium for outcome measures and biomarkers for neurodevelopmental disorders. We are collaborating to cure rare, non-verbal brain disorders.
For a list of clinical trials in this disease area, please click here.