Linear and whorled nevoid hypermelanosis

Get in touch with RARE Concierge.

Contact RARE Concierge

Linear and whorled nevoid hypermelanosis

Synonyms: LWNH

A rare hyperpigmentation of the skin disease characterized by the congenital to infantile-onset of bilateral diffuse (occasionally localized) reticulate (swirls and streaks) macular hyperpigmentation following the lines of Blaschko typically involving the trunk limbs head and neck (but sparing palms soles and mucosa) without preceding inflammation blistering or atrophy. Occasionally extracutaneous abnormalities including autism seizures cardiac defects skeletal abnormalities and developmental delay may be associated. Histologically basal and/or suprabasal melanosis without pigment incontinence is observed.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.

Newly diagnosed with
Linear and whorled nevoid hypermelanosis?

Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.

Get Concierge Help

Advocacy Organizations

Clinical Trials

For a list of clinical trials in this disease area, please click here.