Loeffler endocarditis
Synonyms: Eosinophilic endocarditis
A rare restrictive cardiomyopathy characterized by hypereosinophilia and fibrous thickening of the endocardium with usually large thrombi against the ventricle walls that can lead to cardiovascular complications such as heart failure and thromboembolism. It manifests with symptoms like edema fatigue and shortness of breath. It is usually secondary to eosinophil-associated tissue damage and is associated with idiopathic hypereosinophilic syndrome chronic eosinophilic leukemia carcinoma or lymphoma.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version March 2024
Newly diagnosed with
Loeffler endocarditis?
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Advocacy Organizations
Children’s Cardiomyopathy Foundation
CCF's mission is to accelerate the search for causes and cures for pediatric cardiomyopathy through increased research, education, awareness, advocacy, and support to affected children and their families.
Heart of a Giant Foundation
The mission of the HGF is to achieve better health outcomes for heart diseases and related chronic health conditions in our communities and enhance the quality of life through health education, care support, and connection to community resources.
My Faulty Gene
My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.
Clinical Trials
For a list of clinical trials in this disease area, please click here.