Loeffler endocarditis

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Loeffler endocarditis

Synonyms: Eosinophilic endocarditis

A rare restrictive cardiomyopathy characterized by hypereosinophilia and fibrous thickening of the endocardium with usually large thrombi against the ventricle walls that can lead to cardiovascular complications such as heart failure and thromboembolism. It manifests with symptoms like edema fatigue and shortness of breath. It is usually secondary to eosinophil-associated tissue damage and is associated with idiopathic hypereosinophilic syndrome chronic eosinophilic leukemia carcinoma or lymphoma.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version December 2023

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Loeffler endocarditis?

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Advocacy Organizations

My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

Clinical Trials

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