Lower motor neuron syndrome with late-adult onset

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Lower motor neuron syndrome with late-adult onset

Synonyms: LOSMoN | Late-onset spinal motor neuronopathy | SMAJ | Spinal muscular atrophy, Jokela type

A rare genetic motor neuron disease characterized by slowly progressive predominantly proximal muscular weakness and atrophy which typically manifests with muscle cramps fasciculations decreased/absent deep tendon reflexes hand tremor and elevated serum creatine kinase at onset and later associates with reduced walking ability and impaired vibration sensation.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.

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Lower motor neuron syndrome with late-adult onset?

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Advocacy Organizations

Association Aux Pas du Coeur

Our organization wants to raise awareness and recognize rare diseases in Côte d'Ivoire. Our mission is to: Raising awareness and campaigning to help with the diagnosis and free therapeutic care of patients. Request and/or contribute to actions relating to the training of the medical profession so that doctors are able to make a final diagnosis and ensure the continuous follow-up of patients. Create a patient registry to establish very precise statistics of rare diseases in Côte d'Ivoire. Create a close-knit patient community. Break the isolation and despair of sick people and their families. Open up to the world and actively contribute to international research aimed at treatments.

Clinical Trials

For a list of clinical trials in this disease area, please click here.