Ovarian dysgerminoma
Synonyms: Dysgerminoma of ovary | Dysgerminomatous germ cell cancer of the ovary
A rare malignant germ cell tumor of ovary characterized by a solid lobulated mass usually with a diameter of more than 10 cm generally occurring in children or young women who present with abdominal pain or an abdominal mass and elevated serum LDH. It is bilateral in about 20% of cases although the contralateral tumor may not be evident on macroscopic examination. Histopathologically tumor cells are uniform rounded primitive germ cells with clear cytoplasm and macronucleoli arranged in nests or cords separated by thin fibrous septa containing lymphocytes. Immunohistochemistry should be positive for OCT4 or SALL4 KIT (CD117) and/or D2-40.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Ovarian dysgerminoma?
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