Moderate and severe traumatic brain injury
A rare neurologic condition characterized by brain damage caused by an external mechanical force with a Glasgow Coma Scale score of 9 to 12 in moderate traumatic brain injury (TBI) or 3 to 8 in severe TBI respectively. TBI can be closed (with the dura mater remaining intact) or open (with penetration of the dura mater) and may lead to focal damage such as cerebral contusion and hemorrhage as well as diffuse axonal injury and secondary damage due to increased intracranial pressure. Signs and symptoms are highly variable depending on the nature severity localization and extent of the trauma.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
Newly diagnosed with
Moderate and severe traumatic brain injury?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Moonshots for Unicorns
Curing single-gene disorders
COMBINEDBrain is a consortium for outcome measures and biomarkers for neurodevelopmental disorders. We are collaborating to cure rare, non-verbal brain disorders.
For a list of clinical trials in this disease area, please click here.