Neuroendocrine neoplasm of esophagus

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Neuroendocrine neoplasm of esophagus

Synonyms: Esophageal NEN | Esophageal neuroendocrine neoplasm | NEN of esophagus

A group of esophageal epithelial neoplasms characterized by neuroendocrine differentiation comprising well-differentiated neuroendocrine tumors (NETs) poorly differentiated neuroendocrine carcinomas (NECs) and mixed neuroendocrine-non-neuroendocrine neoplasms an umbrella category including mixed adenoneuroendocrine carcinoma. The tumors typically occur in the lower esophagus often in association with Barrett mucosa. NECs may also arise in other parts of the esophagus. On endoscopy NETs usually appear as small polypoid or nodular submucosal masses while NECs are large infiltrative and ulcerated. Patients most commonly present with dysphagia pain weight loss and sometimes melena. Metastatic NETs may be associated with carcinoid syndrome.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: // Data version September 2023.

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Advocacy Organizations

Neuroendocrine Cancer Awareness Network Inc

The Neuroendocrine Cancer Awareness Network (NCAN) is a non-profit organization dedicated to raising awareness of Neuroendocrine Cancer, providing support for caregivers and people with NETs, and funding for NET cancer research. Since 2003, it has been our mission, or as we like to say, our passion, to educate and support the NET community as a whole. That’s our thing.

My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

My Little Sunshine Foundation

My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.


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Clinical Trials

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