NMDA receptor encephalitis
Synonyms: Limbic encephalitis with N-methyl-D-aspartate receptor antibodies | Limbic encephalitis with NMDA receptor antibodies | N-methyl-D-aspartate receptor encephalitis | NMDARE | anti-NMDA receptor encephalitis
A rare limbic encephalitis characterized by the presence of autoantibodies against NMDA receptors in serum and cerebrospinal fluid. It may be of paraneoplastic (most commonly associated with ovarian teratoma) or non-paraneoplastic origin and is life-threatening but potentially treatable. Patients present with acute behavioral change psychosis and catatonia rapidly progressing to seizures memory deficit dyskinesias speech problems and autonomic and breathing dysregulation.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
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NMDA receptor encephalitis?
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Advocacy Organizations
Encephalitis Society
We are an international charity and the only resource of our kind in the world, dedicated to supporting those affected by encephalitis, their families and professionals involved in their care. Our work involves support, information, awareness and research.
Aicardi-Goutieres Syndrome Advocacy Association
AGSAA is a global coalition of deeply dedicated parent advocates working alongside clinicians, researchers, and scientists. We are united in our desire to improve the lives of individuals and families living with Aicardi-Goutières Syndrome and those yet to be diagnosed. Everything we do reflects a sense of urgency to rescue patient potential and preserve quality of life through accelerating research and providing timely emotional and educational support alongside evolving clinical care recommendations to affected families.
Moonshots for Unicorns
Curing single-gene disorders
COMBINEDBrain Inc
COMBINEDBrain is a consortium for outcome measures and biomarkers for neurodevelopmental disorders. We are collaborating to cure rare, non-verbal brain disorders.
Clinical Trials
For a list of clinical trials in this disease area, please click here.