Nodular cutaneous amyloidosis
Synonyms: PLCNA | Primary localized cutaneous nodular amyloidosis
Primary localized cutaneous nodular amyloidosis (PLCNA) is the most rare form of primary cutaneous amyloidosis (see this term) a skin disease characterized by the accumulation of amyloid deposits in the dermis characterized clinically by yellowish waxy crusted nodules and papules on the face lower extremities trunk scalp and genitalia and histologically by the localized deposition of immunoglobulin-derived amyloid in the papillary dermis and subcutis. PLCNA can be associated with connective tissue disorders such as Sjögrens syndrome and CREST syndrome (see these terms).
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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Nodular cutaneous amyloidosis?
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