Nodular cutaneous amyloidosis

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Nodular cutaneous amyloidosis

Synonyms: PLCNA | Primary localized cutaneous nodular amyloidosis

Primary localized cutaneous nodular amyloidosis (PLCNA) is the most rare form of primary cutaneous amyloidosis (see this term) a skin disease characterized by the accumulation of amyloid deposits in the dermis characterized clinically by yellowish waxy crusted nodules and papules on the face lower extremities trunk scalp and genitalia and histologically by the localized deposition of immunoglobulin-derived amyloid in the papillary dermis and subcutis. PLCNA can be associated with connective tissue disorders such as Sjögren’s syndrome and CREST syndrome (see these terms).

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version May 2024

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Clinical Trials

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