Pemphigus vegetans
A rare autoimmune bullous skin disease characterized by mucocutaneous bullae with subsequent erosion and formation of vegetative plaques predominantly affecting intertriginous areas and the oral mucosa. Two clinical forms of the disease are recognized: the Hallopeau type which presents an indolent course with pustules healing as vegetative plaques and frequent lack of involvement of the oral mucosa and the Neumann type which takes a more severe refractory course with vegetations developing during an eruption of vesiculobullous lesions and involvement of the oral mucosa. Serum analysis reveals antibodies against desmoglein 1 and 3.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Pemphigus vegetans?
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Advocacy Organizations
International Pemphigus & Pemphigoid Foundation
The mission of the International Pemphigus & Pemphigoid Foundation (IPPF) is to improve the quality of life for all people affected by pemphigus and pemphigoid through early diagnosis and support. Our vision is to find a cure for pemphigus and pemphigoid.
The Fairy Goddess Mother Project Inc.
The Fairy Goddess Mother Project is a 501(c)(3) Non-profit Rare Disease Patient Advocacy Organization dedicated to increasing awareness of the little-known, often misdiagnosed disease Vulvar Lichen Sclerosus (VLS), providing financial assistance to afflicted women in need of treatment, and supporting patients’ efforts to participate in clinical trials.
Clinical Trials
For a list of clinical trials in this disease area, please click here.