Pilomatrix carcinoma

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Pilomatrix carcinoma

Synonyms: Calcified epithelial carcinoma of Malherbe | Calcifying epitheliocarcinoma | Malignant pilomatricoma | Trichomatrical carcinoma

A rare skin tumor characterized by an asymptomatic solitary often ulcerated nodule most commonly located in the face involving the deep dermis subcutaneous tissue and skeletal muscle and fascia. Histopathologically the lesion is composed of aggregates of atypical basaloid cells with numerous mitoses. Typical features include shadow cells keratin cysts and trichohyalin and keratohyalin granules. The tumor is locally aggressive and shows a tendency to recur after incomplete excision. Regional lymph node or visceral metastasis has been reported.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.

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My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

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