Pituitary apoplexy

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Synonyms: Pituitary tumor apoplexy

A rare pituitary disease characterized by hemorrhagic or non-hemorrhagic necrosis of the pituitary gland. Clinical manifestations typically comprise sudden and severe headache (often with nausea and vomiting) visual disturbances (visual-field defects loss of visual acuity) oculomotor palsies and variable degrees of altered consciousness ranging from lethargy to coma. Acute endocrine dysfunction may also be present most commonly corticotropic deficiency with severe hypotension and hyponatremia as well as secondary adrenal failure but also thyrotropic and gonadotropic deficiency.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2024

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