Primary autoimmune enteropathy

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A rare intestinal disease characterized by immune-mediated injury of the intestinal mucosa leading to severe chronic intractable diarrhea malabsorption and severe weight loss or failure to thrive. Characteristic histologic findings in the small intestine include partial or complete blunting of the villi deep crypt lymphocytosis increased crypt apoptosis and minimal surface intraepithelial lymphocytosis. In addition the stomach colon and esophagus may also be involved. Circulating autoantibodies against enterocytes and/or goblet cells are found in many but not all patients. The diagnosis requires exclusion of other causes of villous atrophy.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version July 2024

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Primary autoimmune enteropathy?

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Advocacy Organizations

Help Hope Live

Help Hope Live supports community-based fundraising for people with unmet medical expenses and related costs due to cell and organ transplants or catastrophic injuries and illnesses. These efforts play a critical role in helping clients access the care and equipment they need to heal, live, and thrive. Unlock a powerful and safe way to raise funds for medical needs with Help Hope Live. They provide one-on-one fundraising guidance, a customizable Campaign Page, bill pay support, and additional benefits based on their 501(c)(3) nonprofit status.

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Clinical Trials

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