Primary cutaneous diffuse large B-cell lymphoma, leg type

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Primary cutaneous diffuse large B-cell lymphoma, leg type

Synonyms: PCDLBCL,LT

A rare aggressive primary cutaneous B-cell lymphoma characterized by rapidly progressive red to bluish often ulcerating nodular tumors predominantly involving the lower legs. Histology shows sheets of centroblasts and immunoblasts that spare the epidermis but infiltrate the dermis and subcutaneous tissues and often disseminate extracutaneously. The neoplastic cells typically express CD20 CD79a Bcl-2 MUM-1 and FOXP1 but are negative for CD10.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.

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Primary cutaneous diffuse large B-cell lymphoma, leg type?

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Advocacy Organizations

Cutaneous Lymphoma Foundation

We serve as the voice of the cutaneous lymphoma patient community that: Strives to empower people with CL and their care partners through impactful education and support services Influence decisions that can transform lives; and Promote research focused on addressing the most critical unmet needs

Cutaneous Lymphoma Foundation

We serve as the voice of the cutaneous lymphoma patient community that: Strives to empower people with CL and their care partners through impactful education and support services Influence decisions that can transform lives; and Promote research focused on addressing the most critical unmet needs

Youth and Women for Opportunities Uganda-YWOU

Youth and Women for Opportunities-YWOU an organization that we represent is patient organization re-presentative, patient and institution and individual capacity builder supporting PLWRD’s to obtain diagnosis, treatment and drugs for those suffering consequences of being undiagnosed or misdiagnosed and lack treatment and those who lack precise diagnosis for rare, orphan and undiagnosed diseases preventing PLWRD’s accessing the most adapted care, treatment or surgery, have delayed access to the most appropriate care, treatment or surgery

My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

My Little Sunshine Foundation

My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.

SALUS

Educate and provide resources to POC with Rare Cancers

Clinical Trials

For a list of clinical trials in this disease area, please click here.