Secondary non-traumatic avascular necrosis
Synonyms: Secondary non-traumatic AVN | Secondary non-traumatic osteonecrosis
A rare osteonecrosis disease characterized by death of bone cellular components secondary to an interruption of the subchondral blood supply typically manifesting with unilateral or bilateral unifocal or multifocal lesions usually located on the epiphysis metaphysis and/or diaphysis of the femoral heads knees shoulders ankles and/or wrists leading to gradual onset of pain and progressive joint degeneration resulting in loss of function. Association with corticosteroid usage alcoholism hyperbaric events radiation or cytotoxic agent exposure hemoglobinopathies and/or underlying autoimmune or metabolic disease amongst others has been observed.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Secondary non-traumatic avascular necrosis?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Clinical Trials
For a list of clinical trials in this disease area, please click here.