Sepsis in premature infants

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Sepsis in premature infants

A rare systemic condition affecting neonates born at less than 37 weeks gestational age and characterized by life-threatening organ dysfunction caused by a dysregulated host response to an infection which may have been acquired shortly before or during birth (resulting in early-onset neonatal sepsis during the first 72 hours of life) or after birth (leading to late-onset neonatal sepsis between 72 hours and three months). Prematurity constitutes one of the primary risk factors for neonatal sepsis. The clinical picture may develop gradually with signs and symptoms like irritability lethargy or poor feeding or progress rapidly to respiratory distress fever hypothermia hypotension shock and multiple organ failure.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024

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Clinical Trials

For a list of clinical trials in this disease area, please click here.