Sporotrichosis

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Sporotrichosis is an infection caused by the dimorphic fungus Sporothrix schenckii generally occurring by traumatic inoculation of fungus from contaminated soil plants and organic matter that has a highly variable disease spectrum but that usually presents as a subcutaneous mycosis with a single sporotrichotic chancre that may ulcerate and can then progress to lymphocutaneous (most common form; sporotrichotic chancre at inoculation site and a string of similar nodules along the proximal lymphatics) fixed cutaneous (localized asymptomatic erythematous papules at the inoculation site) or multifocal or disseminated cutaneous (rare form with 3 or more lesions involving 2 different anatomical sites) forms. Pulmonary sporotrichosis occurs following inhalation of fungus and manifests as chronic pneumonitis while extracutaneous or systemic sporotrichosis (with osteoarticular pulmonary and central nervous system/meningeal disease) has also been reported usually occurring in the setting of immunosuppression.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version May 2024

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