Squamous cell carcinoma of the penis

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Synonyms: Penile squamous cell carcinoma

A rare urogenital tumor characterized by origin from squamous epithelial cells of the penis most commonly the glans or inner surface of the prepuce. Macroscopically the tumors can appear either papillary or flat and ulcerating. Histological subtypes include usual squamous cell carcinoma as the most common type as well as basaloid warty verrucous papillary and mixed carcinomas. Patients may initially be asymptomatic but present with itching bleeding discharge foul odor and pain as the disease progresses. Regional lymph node involvement is common while distant metastases occur only late in the disease. Risk factors include HPV infection smoking poor hygiene and HIV infection. Neonatal circumcision is implicated as strongly protective.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2024

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My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

My Little Sunshine Foundation

My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.


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