Squamous cell carcinoma of the penis
Synonyms: Penile squamous cell carcinoma
A rare urogenital tumor characterized by origin from squamous epithelial cells of the penis most commonly the glans or inner surface of the prepuce. Macroscopically the tumors can appear either papillary or flat and ulcerating. Histological subtypes include usual squamous cell carcinoma as the most common type as well as basaloid warty verrucous papillary and mixed carcinomas. Patients may initially be asymptomatic but present with itching bleeding discharge foul odor and pain as the disease progresses. Regional lymph node involvement is common while distant metastases occur only late in the disease. Risk factors include HPV infection smoking poor hygiene and HIV infection. Neonatal circumcision is implicated as strongly protective.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Squamous cell carcinoma of the penis?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Clinical Trials
For a list of clinical trials in this disease area, please click here.