Talo-patello-scaphoid osteolysis
Synonyms: Singh-Williams-McAlister syndrome
Talo-patello-scaphoid osteolysis is an extremely rare form of primary osteolysis (see this term) described in two sisters to date characterized by bilateral osteolysis of the tali scaphoids and patellae (accompanied by periarticular swelling and pain) and short fourth metacarpals (brachydactyly type E; see this term) in the absence of renal disease. Autosomal recessive inheritance has been suggested.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Talo-patello-scaphoid osteolysis?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
The Chandler Project
The Chandler Project brings awareness and shines a light on transformative research surrounding achondroplasia and other skeletal dysplasias by offering support to a global community and network of patients, parents, and caregivers seeking information on scientific discoveries, pharmaceutical advancements and surgical treatment options.
Clinical Trials
For a list of clinical trials in this disease area, please click here.