Transgrediens et progrediens palmoplantar keratoderma
Synonyms: Greither disease | Keratosis extremitatum hereditaria progrediens | Keratosis palmoplantaris transgrediens et progrediens | Progressive diffuse PPK | Progressive diffuse palmoplantar keratoderma | Transgrediens et progrediens PPK
A rare isolated diffuse palmoplantar keratoderma disorder characterized by red-yellow moderate to severe hyperkeratosis of the palms and soles extending to the dorsal aspects of the hands feet and/or wrists and involving the skin over the Achilles’ tendon (transgrediens) gradually worsening with age (progrediens) to include patchy hyperkeratosis over the shins knees elbows and sometimes skin flexures. Hyperhidrosis is usually associated. Histologically either epidermolytic or nonepidermolytic changes may be seen.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Transgrediens et progrediens palmoplantar keratoderma?
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