Wolfram-like syndrome
Wolfram-like syndrome is a rare endocrine disease characterized by the triad of adult-onset diabetes mellitus progressive hearing loss (usually presenting in the first decade of life and principally of low to moderate frequencies) and/or juvenile-onset optic atrophy. Psychiatric (i.e. anxiety depression hallucinations) and sleep disorders the only neurologic abnormalities observed in this disease have been reported in rare cases. Unlike Wolfram syndrome patients with Wolfram-like syndrome do not report endocrine or cardiac findings.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
Newly diagnosed with
Wolfram-like syndrome?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
Clinical Trials
For a list of clinical trials in this disease area, please click here.