X-linked acrogigantism

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X-linked acrogigantism

Synonyms: Familial infantile gigantism | Hereditary infantile gigantism | Hereditary pituitary hyperplasia | Infantile gigantism due to pituitary hyperplasia | X-LAG

A rare genetic pituitary disease characterized by infantile-onset rapid and excessive acceleration of linear growth and body size due to mixed growth hormone (GH)- and prolactin-secreting adenomas and/or pituitary hyperplasia. Patients present with gigantism and may have associated acromegalic features (e.g. coarse facial features frontal bossing prognathism increased interdental space) as well as marked enlargement of hands and feet soft tissue swelling increased appetite and acanthosis nigricans.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version December 2023

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X-linked acrogigantism?

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